Category: Bariatric surgery

FDA Reverses Position on Tirzetapide Shortages; UK NHS Tackles Obesity; Telehealth GLP-1 Gold Rush; Superior Outcomes with Bariatric Surgery

AT A GLANCE Endpoints News leads with the surprising twist, that the FDA said it would rethink ending the shortage of Eli Lilly’s weight loss drug tirzepatide. The UK National Health Service receives a £279 million boost to tackle significant health challenges, from Eli Lilly. Greg Justice at asteriskmag asks How Long Till We’re All on Ozempic? An unprecedented online cash grab powering telehealth’s GLP-1 ‘gold rush’ is reviewed by

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Metsera’s-Long-Acting-GLP-1

Metsera’s Long-Acting GLP-1; Mount Sinai Partners with Noom; Wegovy and Medicare Price Negotiations; New Guidelines for Bariatric Surgery; WeightWatchers CEO is Out.

AT A GLANCE STAT’s Elaine Chen on Novo Nordisk’s trial of cannabinoid CB1 receptor inhibitor monlunabant, with modest 6.4% weight loss and some psychiatric side effects. Metsera announced phase 1 clinical trial results of MET-097, a long-acting injectable GLP-1 drug with weight reduction of 7.5% at day 36. Modern Healthcare on Mount Sinai partnering with Noom, aimed at behavioral approaches to weight loss. Medicare spent $5.6B on

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Roche’s-New-Oral-GLP-1-Med

Roche’s New Oral GLP-1 Med; Closure of Oklahoma Bariatric Surgery Clinic; Personalized Nutrition; Sleep Apnea and GLP-1s; 15 Years Later, Bariatric Surgery Works.

AT A GLANCE Roche announced its once-daily pill, CT-996, led to weight loss of 6.1% after four weeks in patients with obesity who did not have diabetes, as per STAT. The Oklahoman reports ‘…Norman Regional Health System is blaming the diabetes management drug and similar medications… for the decision to suddenly close its Journey Clinic.’ Rock Health, together with real-world data company Evidation, undertook a

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24% Reduction in Kidney Events on Semaglutide; TikTok bans Weight Meds Marketing; Bariatric Surgery Cures Infertility; 50% Discontinue GLP-1s at 1y.

24% Reduction in Kidney Events on Semaglutide; TikTok bans Weight Meds Marketing; Bariatric Surgery Cures Infertility; 50% Discontinue GLP-1s at 1y.

AT A GLANCE The American Heart Association ‘…highlights the barriers to treatment and improvements needed in translating the science of obesity to patient care.’ Daniel Gilbert at The Washington Post reports on the ban of TikTok star Taylor Huber who is paid to promote weight-loss medications. The New England Journal of Medicine reports a 24% reduction in kidney disease events, or death from kidney-related or cardiovascular

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‘South Park’ on Obesity; Novo Trial on Alcoholic Liver Disease; Bernie Sanders Blasts Wegovy Prices; Bariatric Surgery Protects Against Breast Cancer.

‘South Park’ on Obesity; Novo Trial on Alcoholic Liver Disease; Bernie Sanders Blasts Wegovy Prices; Bariatric Surgery Protects Against Breast Cancer.

AT A GLANCE ‘It’s time for some drastic measures to bring down his weight…’ says the doctor in the trailer for South Park: The End of Obesity. STAT on Novo Nordisk to test GLP-1 drugs for people with alcohol-associated liver disease. The Hill on Senate Health Committee Chair Bernie Sanders stating Wegovy could bankrupt US health system. JAMA on bariatric surgery protection against development of breast cancer. STAT on

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Eli-and-Novo-beat-Q1-Earnings;-Amgen’s-Monthly-Injectable-GLP-1-Candidate;-Ozempic-Babies;-Bariatric-Surgery-Impacts-Kidney-Transplant-Rates

Eli and Novo beat Q1 Earnings; Amgen’s Monthly Injectable GLP-1 Candidate; Ozempic Babies; Bariatric Surgery Impacts Kidney Transplant Rates.

AT A GLANCE Amgen to focus on MariTide, an monthly injectable monoclonal antibody, rather than AMG 786, its early-stage obesity pill, from STAT News. Elaine Chen at STAT notes Eli Lilly raised its full-year guidance on Tuesday while it reported strong first-quarter sales of Zepbound. The Wall Street Journal reports sales of Wegovy more than doubled in the first quarter. Online pharmacies and slimming clinics are cutting prices

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Costco’s Weight Loss Program; China Develops GLP-1 Drug; Not Everyone Loses Weight on Ozempic; Weed for Weight Loss; GLP-1 For Parkinson’s

Costco’s Weight Loss Program; China Develops GLP-1 Drug; Not Everyone Loses Weight on Ozempic; Weed for Weight Loss; GLP-1 For Parkinson’s

AT A GLANCE USA Today reports ‘…Costco and its low-cost health care partner are expanding into weight-loss management…’ Reuters notes a biosimilar version of Novo Nordisk’s popular diabetes drug Ozempic has been developed in China Sumathi Reddy at The Wall Street Journal writes some people don’t lose much weight on drugs like Ozempic. Dr. Amir Ghaferi and colleagues from Wisconsin review Metabolic Surgery for Diabetes Management

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Wegovy for Medicare Beneficiaries; Bariatric Surgery Restrictions Eased by GLP-1 Costs; $6B Spend on GLP-1s by Medicare in 2022; $5 Per Month to Manufacture Ozempic; Viking Therapeutics Stock Charges

Wegovy for Medicare Beneficiaries; Bariatric Surgery Restrictions Eased by GLP-1 Costs; $6B Spend on GLP-1s by Medicare in 2022; $5 Per Month to Manufacture Ozempic; Viking Therapeutics Stock Charges

AT A GLANCE San Diego biotech Viking Therapeutics shares were up 20% on news that the oral version of dual GLP-1/GIP drug VK2735 had succeeded its phase 1 trial. Peter Loftus at The Wall Street Journal reports CVS Health, Elevance Health and Kaiser Permanente would cover Wegovy for Medicare beneficiaries. Miriam E. Tucker at Medscape suggests ‘GLP-1 Costs May Ease Restrictions to Bariatric Surgery.’ The Kaiser Family Foundation analyzed Medicare

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A Billion People Obese Worldwide; An Obesity Vaccine? – from Novo Nordisk and Vivani; Survodutide for Liver Disease; Bariatric Surgery Cures Diabetes

A Billion People Obese Worldwide; An Obesity Vaccine? – from Novo Nordisk and Vivani; Survodutide for Liver Disease; Bariatric Surgery Cures Diabetes

AT A GLANCE STAT reports on Marcus Schindler, Novo’s chief scientific officer, who wants to ‘…make long-lasting GLP-1 molecules…’ with ‘…vaccine-like properties.’ NPM-115 and NPM-139 are miniature, subdermal GLP-1 implants from NASDAQ-listed company Vivani Medical, Inc. that provide once- or twice-yearly administration. STAT reports from a study in The Lancet that ‘…more than 1 billion people – or one in eight people worldwide –

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Obamacare and GLP-1 meds; China’s Obesity Crisis; India’s GLP-1 Drugmakers; Bariatric Surgery cures Diabetes; Corporate Ozempic

Obamacare and GLP-1 meds; China’s Obesity Crisis; India’s GLP-1 Drugmakers; Bariatric Surgery cures Diabetes; Corporate Ozempic

AT A GLANCE STAT reports ‘…Obamacare insurance is considering a technical change that would require insurers to cover obesity drugs in a market of more than 20 million Americans.’ Goldman Sachs analysts are featured by Reuters that weight-loss drugs ‘…could boost gross domestic product by 1%.’ Marketing guru Scott Galloway writes ‘…Nobody I know is on Ozempic. Yet, nearly everyone I know is on Ozempic.’ The Wall Street Journal notes China

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